Detection of risk factors for the development of catheter-related bloodstream infections and catheter-related thrombosis in patients with peripherally inserted central venous catheters: a scoping review
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Accepted: 21 July 2025
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Introduction: in recent decades, the Peripherally Inserted Central Venous Catheter (PICC) has been recognized as an effective and safe vascular access device. Despite the great advantages, PICC are not free from complications. The most common complications include Catheter-Related Bloodstream Infections (CRBSI) and Catheter-Related Venous Thrombosis (CRT). The literature still lacks a comprehensive synthesis of the multiple factors associated with these complications and shows considerable heterogeneity in CRBSI and CRT rates. This scoping review aims to identify the causes that determine the onset of complications.
Materials and Methods: the following databases were consulted: PubMed, CINAHL, Scopus and Web of Science. Study selection and data extraction were performed independently by two authors.
Results: 19 final articles allowed us to identify factors related to the implant, the patient or the management that affect the onset of complications. Insertion technique, choice of vascular device, patient pathology and therapy were found to be key factors in the development of complication rates.
Discussion: Knowledge of the root causes of PICC complications is essential to improve clinical practice and patient outcomes. Further studies are needed to analyze how the experience of implanters affects complications.
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